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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5bead53a0d6875c204760a93962bcdacd9ea59df868ed8ff4657931d78ba8b' 
  AND token = 'k3p+M/Yj36wLyS8CyEENjMVKB444t8kBiDfsE1nn2IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}