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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31f9d53e6c63a4f0429e2b53de3e49db27c95ec100a560d560a42d34094b2c37' 
  AND token = 'yiqxM2CAQy2aXcT5KTENK+uh9IcPW1GTu8iM6RvQzbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}