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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151fcb8987b4e43ca5c5b01ebe9e0d769d065b6b49f7a639c2fce6a08d7e1f22' 
  AND token = '5yTEE7A4MXpCAAfdNK+fq8j+qQmONz6Y3xsvQcUbhyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}