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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d044ad37b106e172248c78e8e2b89d44546fbe19ce00d7ab9491f457fa573b' 
  AND token = '+uiMasfYf6DjcLcYbDA+Bfpf4QQBBSfTC+GZeZofXq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}