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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641d881eea937460b7b27de83cfd438084ea15b81b5b8d6e5b7677c10aa6f012' 
  AND token = '5WVTYEnuiiL9cDQjLakxWVDY9y+sf68hlHuimKUBoYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}