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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f49263716ec6c74404541d538f6035cc7ea17df49e4b04e8ee4940929cd9880' 
  AND token = 'NxCTzKYO385Y0ityIr94m+zmZhxoLxBu02y/B0w9xOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}