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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b19531182b6b45bf951068644cadfd476c01876a2fbe96c4fb9f6c5066716887' 
  AND token = 'NFghmN42Ydoho/Zz8PeDn9P/btUTQwxFEZqZGRk/1to=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}