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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e4a4c793e399f1af8a41a38525d3ddeecdf76b9eeb2a6745c87e98b659508cd' 
  AND token = 'SE7CErHSSmcaBcQqIFVGxzLQVpSZyXdNQK9tVQvBU5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}