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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '296f72d1d8772a457198f689bc7c5c10574955e12992ab0189999ada7edab8ac' 
  AND token = 'NBQl2nufLogrnJM7JAVGIsDPCkrV0HlejjGdCxba+9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}