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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78bf367b805c4bd35f871b0a1861f56eb712c93f617bb6c6ebc58d0b78354a39' 
  AND token = 'yJfSEG22RqGNWUWeffcKF6c1BfkTazy65R1l6nlvLP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}