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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd892278a0d7969204b9c0700f1e02a5aabcba58d347ea2a45afbd74e3c8125' 
  AND token = 'ziq3mbdyaYojFrq67qGiYwae0X0GHY3XDOkYm+uj2Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}