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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f925b0d90bdc05a986919da1016996cf6ea453200661819f33b71823d0bf4ffe' 
  AND token = 'htAZ3Af0POwCM7mcG796T0q6Lfhp3yRyELB34/e7QmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}