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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac495f0ab696f159a928a73700a0fddabd26118e7d9c32c34240439adb76aa5c' 
  AND token = 'awNGn2gTEBMnVvy5iJ2CpWxfxAYe+wwXbO3wpzz1gUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}