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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005642c23189c2687640bfe9364fd490edf4af4b35d1cea1b55d55c1aa688767' 
  AND token = '01cXz2CVEndMUP33Iig/Gipdec57wuREm1+6g0b911A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}