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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781c9422a7280df3f35246d04212dc24508e543d8900f4da0d2a59a233c412e6' 
  AND token = 'WtukP/7aqfQqUr1IPdPcj6Yy1R1bzsYuQI7agpmERiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}