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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a780eb29404cbf37952858e58dc46a02611620aa84b3c64e757ba838f1d2ac' 
  AND token = '9UKDo3qWCflszUNKiwDbIB0HOR1H3dpG0HbRyQ+Qr9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}