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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '348eb06ff847a7ab1bca8432086b31738e068e2292360218d3dbb00e0839e99e' 
  AND token = 'cun23tNHUehTMyYAwfvQ8obFjrqVsw6mTQqgXJGRL3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}