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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51c4546b66f9c7524e71f58a29e54df2e38419dc82eadb191cb0c3113e1f371e' 
  AND token = 'wVM8xpInn/rMNbDq8vPerghG+7kYxqHMsDdd77j3V5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}