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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f9280fbee7fbf425c8a98a827975925f67ee99b856bde37443797c67152144' 
  AND token = 'qabRD59Sd8wjLKP8kDt/Vg2TV6e3hPtstZZngKcqUV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}