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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b2d031202d829c024588536abbb9cfca0429110cda82e8308a741cf8f96038' 
  AND token = '3BZs3oCbb6ND1Y36YA/ixy5l2oF2W48J9JWQmMvVLrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}