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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82fed21478dd687f240ae88ad2e9f3d2fd9d213843eced45d6c654a33a80c8ec' 
  AND token = '3SCgpt0R82EJQMJpYc1uYVRxUXLOQPqaFTB9oyL9mFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}