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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd294b3d6dbe5707e1c962b77f1de55bbd6ab178dfc777f95cfa6cb4cd377e6a8' 
  AND token = '8AG65JgmsULf/MchdCkeAncx5aQhsdSMIXgAtKD3MQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}