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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d274404c76f1afd2e34867428b7cd5b580e2b93b5763341ff6df8afbd1e1d1' 
  AND token = '5/8RWHMG00ALI3pBWzMNcOloJv5v5s3otcHgCJiFMxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}