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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303121e726cee3e1cf25150936559dfc8ec9996369b539e2a30650d422ae747c' 
  AND token = 'cFsAabwCZZVC/RKaUTKeYh8HSgRWZkjF7+ZrbwOd1Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}