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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfac1a9f34d221272f44a94f5674fcccb1f49e279f02ad21bbbb26087a0f4b46' 
  AND token = 'a+k3FEwpYhbsgdOfvfd1hLMV+iQQ7aOLBct1PwTnc8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}