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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f068783299fec1c4141dca8c2d20fc32acce123d736329e77959ddb0fe264d' 
  AND token = 'HYtbwQ3vi1w29DLoaakXl/U9zhYi5OOtRd7SMPAK5S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}