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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5221c95409b56900521406296ccd314804961ccef2acceb5374f5ea8287d264' 
  AND token = '5k2aH5G9BiYc5FxZ/Mj3PwzjTfeg4xeop20E4DJ6R2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}