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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5248853418b20125f121139e04a83fe3d76845d1fdd7655dd2f5f46615d8d7' 
  AND token = 'TVPBUINoX9ULYrKiPn6wvOVHTcZ44s0BM9VVbkZUKI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}