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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a39825478ed73bfaa10382587dacbe629a2716d2e41d91a614cd9a739997c25e' 
  AND token = 'JhCU/DQIeScvS4kyMRK2ur9r+N0NZVqRYZdqVL1UNo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}