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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27670c2e6111876cd98a75cf5b1fb1499de002840451d99dc5574e742a32c09f' 
  AND token = 'ihlAsL17E7ur7RKPaFKegsrHSMeB7RTw0nTiBeaD/DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}