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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5483aaa0a57c4ea780b77871a207097a688dd97b96ae250221e8e23322b23d' 
  AND token = 'kf+HT+4AmF71cg1NHaXNqbYeD+EaWmompOCAGeoE8pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}