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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bd63ddb48c14c9ffa4c8f561096d502d986a0a88e79a3e307ef42371328fc7e' 
  AND token = 'yYlAoTP7l4NYWET9bx/h4iP5W7UUFqq6qmokOEtsgys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}