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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a47142cee1fa6e0e1da13554a94d0a4398ad3860fa01ee9b2d0b705a184ed587' 
  AND token = 'URiOVrm6yeQdoyaB6vkl/eAH3JorA+0blCPgo8w9wHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}