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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a283901bf4e581e185002daae1969b442fbea29dcf685f7cd4c2a61e9a4a27' 
  AND token = 'NoFE8u7AFcXJvow6QTI+mBwFUEIS9dg6yV9m9QkhT34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}