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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bb2d1f6b74a6f19a5d5392953669b40ee0ac1c3c7f11acae66ba3f10f9eb479' 
  AND token = 'PxNX6Gn9p8PxSG2zCmA5Y9iSwsSQF6towhQTvV5ZVDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}