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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c3bf855f1b3bc5d0f9a8e9e0dded01218e2d1a03df47268631de76d7337095' 
  AND token = 'pgHuGQxB7cP8du7K9qq/pEgUki3nJOe+jnS7hm0AyrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}