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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4b0a2ea54c5f56b80e130e4ee9eee2869f9400537104ff01e63f4ccb5c501a' 
  AND token = 'xXhWyps3+dWiV/tr58RIsFd/eBjPFDNMWBdDKo5UnM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}