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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '916e08203bb75529e543b4e7e5a7742293f980e3e87811069993f5c3c3be4730' 
  AND token = 'hWhR8y7ZbM+x17LKSG6lcx3WCvlP+7hDf/uBVyGr2QE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}