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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c26267b96cba03ee5ca1fdbb66becb473b71c3475a29b4aaf96c3d9748610a4a' 
  AND token = 'TRM1ARr2b5dnT3GLA6snGQf8UgpfUjsr/J2dSk9AdoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}