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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c945cf9628122a7d3e0a4ebb3b1c34c71ce258c426b8f4d49897ffd8bdda77' 
  AND token = 'rE8SzpkuhhPnLtbdQlGjsiO3sFrdUnFaQgTgJZh22hU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}