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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0e17526d34dc2bc599e44f3ef7d48612f3b728b5ff42cf43ccb9da89106d14' 
  AND token = '46yautHkswhy/ezo5e/2gZCm8rQOEebccW0r/VeoziE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}