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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d3259492ec6c3b1143d0feb92fd86cdc3bf565261556e3e70f478732967e016' 
  AND token = '1//Dz8s2avtDzZ/GwGIGoDNO2W38sHM+ciBGiGVgDbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}