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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0321b3f96036249b3b3cef4bdb2df439de7a9c2e644abd39e0e5b037c0535bbb' 
  AND token = '1zLQrWtFXEnKFkpLc3y2Ib9z8sKiR5OGp7h1qq5aKeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}