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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdeea67428d02aa36fb977c34dbed462b03b57f73637d78f600f408d9061fda4' 
  AND token = 'JVsTmPPrkRG7nkRG1hLyizBw0CeW+4WWGQLByHFG/MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}