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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c00678e59a267dfd4b8ab5ab00059f0b857edbbd7240cd639b03b32f5873b33' 
  AND token = 'ITvm1r4UNBhcXe7Pap6RtK5cABE21TVAH82YBHu7F28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}