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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '677148d5e3ca76f3c998ffe4b20ef323eb3c8f1f773fa4024c0805f1904d1251' 
  AND token = 'aquTXfXqjVvcV5fJ3itCGasuwAnH2ZtlxfIOwTYKeyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}