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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53623a2d2a011201a836d8d5cd81b3f4aa819f33c6b262245703180c39c308ea' 
  AND token = 'i6dxLwzLwbQVIE5sXyTaKYWhxlr6XE9NfG9fEPv09HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}