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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8a740caaddfbef8bf7f7576385941f430664eeb3ebac648bdf586df6d7ccd9' 
  AND token = '5iZcq3aqqUNGVoDy6qnKk3/V7f0HqnAGzXSmkKBxMcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}