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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09397b17476cb84f71f741d6cc8f6be8e7baf63dd9feb2647ce59ace7a76dce3' 
  AND token = 'nEBsb1a0KFuc+Mpk8zPNZIS0qX36FpxgwqeehFMBxA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}