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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4fa128e527663cec919fabe978f56ef281007da99cd8fb187a77d74b78899a' 
  AND token = 'JQB/KsnLDyd24i2/YE6gPKbP67iwH+WZG/CbMWaQTmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}